It is the 846th drug that the Massachusetts lab ALS TDI has tried since 1999 to slow the progression of ALS.

And the first to work in lab mice. It’s expected to go to human trials next year, and Nieto hopes to be part of those trials.

“It’s the biggest thing that’s ever happened in ALS,” say Nieto and his wife Lynne – who themselves have been the biggest fundraisers in the history of the disease.

See the full article here. More information on 00846 can be found here.